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FACTIVE (GEMIFLOXACIN MESYLATE) TABLETS: MEDICATION GUIDE - SIDE EFFECTS
What are the possible side effects of Gemifloxacin Mesylate (Factive) tablets?
Factive can cause side effects that may be serious or even cause death.
Other serious side effects of this medication include:
Central Nervous System Effects. Seizures have been reported in people who take fluoroquinolone antibiotics, including Factive (Gemifloxacin) pills. Tell your healthcare provider if you have a history of seizures. Ask your healthcare provider whether taking Factive will change your risk of having a seizure.
Central Nervous System (CNS) side effects may happen as soon as after taking the first dose of Factive (Gemifloxacin Mesylate) pills. Talk to your healthcare provider right away if you get any of these side effects, or other changes in mood or behavior:
- feel lightheaded
- hear voices, see things, or sense things that are not there (hallucinations)
- feel restless
- feel anxious or nervous
- trouble sleeping
- suicidal thoughts or acts
- feel more suspicious (paranoia)
Serious allergic reactions. Allergic reactions can happen in people taking fluoroquinolones, including Factive, even after only one dose. Stop taking Gemifloxacin (Factive) pills and get emergency medical help right away if you get any of the following symptoms of a severe allergic reaction:
- swelling of the lips, tongue, face
- trouble breathing or swallowing
- throat tightness, hoarseness
- rapid heartbeat
- yellowing of the skin or eyes. Stop taking Factive and tell your doctor right away if you get yellowing of your skin or white part of your eyes, or if you have dark urine. These can be signs of a serious reaction to Factive (a liver problem).
Skin rash. Skin rash may happen in people taking Gemifloxacin Mesylate (Factive) pills. Stop taking this drug at the first sign of a skin rash and call your healthcare provider. Skin rash may be a sign of a more serious reaction to Factive. Rash happens more often with this medicine in:
- women, especially women who take hormone replacement therapy
- people under 40 years of age
- people who take Factive (Gemifloxacin) for longer than 5 days.
Serious heart rhythm changes (QT prolongation and torsades de pointes). Tell your healthcare provider right away if you have a change in your heartbeat (get a fast or irregular heartbeat), or if you faint. Factive may cause a rare heart problem known as prolongation of the QT interval. This condition can cause an abnormal heartbeat and can be very dangerous. The chances of this happening are higher in people:
- who are elderly
- with a family history of prolonged QT interval
- with low blood potassium (hypokalemia)
- who take certain medicines to control heart rhythm (antiarrhythmics).
Intestine infection (Pseudomembranous colitis). Pseudomembranous colitis can happen with most antibiotics, including Factive. Call your doctor, pharmacist, or other healthcare professional right away if you get watery diarrhea, diarrhea that does not go away, or bloody stools. You may have stomach cramps and a fever. Pseudomembranous colitis can happen 2 or more months after you have finished your antibiotic.
Changes in sensation and possible nerve damage (Peripheral Neuropathy). Damage to the nerves in arms, hands, legs, or feet can happen in people taking fluoroquinolones, including Gemifloxacin (Factive). Talk with your healthcare provider right away if you get any of the following symptoms of peripheral neuropathy in your arms, hands, legs, or feet:
Factive may need to be stopped to prevent permanent nerve damage.
Sensitivity to sunlight (photosensitivity).
The most common side effects of Factive (Gemifloxacin Mesylate) include:
These are not all the possible side effects of Factive. Tell your healthcare provider about any side effect that bothers you or that does not go away.
Call your doctor for medical advice about side effects. You may report side effects to U.S. FDA.
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Factive medication guide